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KOMP Repository (Knockout Mouse Project) KOMP Knock Out Knockout Mouse Mice
GO Terms found for Rapgef1
Rap guanine nucleotide exchange factor (GEF) 1:

Biological Process GO:0001568 blood vessel development
Biological Process GO:0010976 positive regulation of neuron projection development
Biological Process GO:0032486 Rap protein signal transduction
Biological Process GO:0038180 nerve growth factor signaling pathway
Biological Process GO:0043547 positive regulation of GTPase activity
Biological Process GO:0046328 regulation of JNK cascade
Biological Process GO:0046580 negative regulation of Ras protein signal transduction
Biological Process GO:0048008 platelet-derived growth factor receptor signaling pathway
Biological Process GO:0051898 negative regulation of protein kinase B signaling
Biological Process GO:0061028 establishment of endothelial barrier
Biological Process GO:0070373 negative regulation of ERK1 and ERK2 cascade
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0071320 cellular response to cAMP
Biological Process GO:0090090 negative regulation of canonical Wnt signaling pathway
Biological Process GO:0090630 activation of GTPase activity
Biological Process GO:0098609 cell-cell adhesion
Biological Process GO:1901888 regulation of cell junction assembly
Biological Process GO:1905451 positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
Biological Process GO:1990090 cellular response to nerve growth factor stimulus
Biological Process GO:2000178 negative regulation of neural precursor cell proliferation
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005769 early endosome
Cellular Component GO:0030670 phagocytic vesicle membrane
Cellular Component GO:0032991 protein-containing complex
Cellular Component GO:0043231 intracellular membrane-bounded organelle
Cellular Component GO:0048471 perinuclear region of cytoplasm
Cellular Component GO:0005829 cytosol
Molecular Function GO:0005070 SH3/SH2 adaptor activity
Molecular Function GO:0005085 guanyl-nucleotide exchange factor activity
Molecular Function GO:0005515 protein binding
Molecular Function GO:0017034 Rap guanyl-nucleotide exchange factor activity

Gene - GO associations are updated daily from MGI

The KOMP Repository Collection is located at the MMRRC at the University of California, Davis and Children’s Hospital Oakland Research Institute. Question? Comments? For Mice, Cells, and germplasm please contact us at mmrrc@ucdavis.edu, US 1-888-KOMP-MICE or International +1-530-752-KOMP, or for vectors komporders@chori.org or +1-510-450-7917.