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KOMP Repository (Knockout Mouse Project) KOMP Knock Out Knockout Mouse Mice
GO Terms found for Pten
phosphatase and tensin homolog:

Biological Process GO:0001525 angiogenesis
Biological Process GO:0001933 negative regulation of protein phosphorylation
Biological Process GO:0002902 regulation of B cell apoptotic process
Biological Process GO:0006470 protein dephosphorylation
Biological Process GO:0006629 lipid metabolic process
Biological Process GO:0006915 apoptotic process
Biological Process GO:0007270 neuron-neuron synaptic transmission
Biological Process GO:0007399 nervous system development
Biological Process GO:0007416 synapse assembly
Biological Process GO:0007417 central nervous system development
Biological Process GO:0007507 heart development
Biological Process GO:0007611 learning or memory
Biological Process GO:0007613 memory
Biological Process GO:0007626 locomotory behavior
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0010666 positive regulation of cardiac muscle cell apoptotic process
Biological Process GO:0010719 negative regulation of epithelial to mesenchymal transition
Biological Process GO:0010975 regulation of neuron projection development
Biological Process GO:0010977 negative regulation of neuron projection development
Biological Process GO:0016311 dephosphorylation
Biological Process GO:0016477 cell migration
Biological Process GO:0021542 dentate gyrus development
Biological Process GO:0021955 central nervous system neuron axonogenesis
Biological Process GO:0030336 negative regulation of cell migration
Biological Process GO:0030534 adult behavior
Biological Process GO:0031175 neuron projection development
Biological Process GO:0031642 negative regulation of myelination
Biological Process GO:0031647 regulation of protein stability
Biological Process GO:0032228 regulation of synaptic transmission, GABAergic
Biological Process GO:0032286 central nervous system myelin maintenance
Biological Process GO:0032535 regulation of cellular component size
Biological Process GO:0032869 cellular response to insulin stimulus
Biological Process GO:0033032 regulation of myeloid cell apoptotic process
Biological Process GO:0033137 negative regulation of peptidyl-serine phosphorylation
Biological Process GO:0033555 multicellular organismal response to stress
Biological Process GO:0035176 social behavior
Biological Process GO:0036294 cellular response to decreased oxygen levels
Biological Process GO:0042711 maternal behavior
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0043491 protein kinase B signaling
Biological Process GO:0043542 endothelial cell migration
Biological Process GO:0044320 cellular response to leptin stimulus
Biological Process GO:0045475 locomotor rhythm
Biological Process GO:0045666 positive regulation of neuron differentiation
Biological Process GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
Biological Process GO:0045792 negative regulation of cell size
Biological Process GO:0046621 negative regulation of organ growth
Biological Process GO:0046855 inositol phosphate dephosphorylation
Biological Process GO:0046856 phosphatidylinositol dephosphorylation
Biological Process GO:0048008 platelet-derived growth factor receptor signaling pathway
Biological Process GO:0048679 regulation of axon regeneration
Biological Process GO:0048681 negative regulation of axon regeneration
Biological Process GO:0048738 cardiac muscle tissue development
Biological Process GO:0048853 forebrain morphogenesis
Biological Process GO:0048854 brain morphogenesis
Biological Process GO:0050680 negative regulation of epithelial cell proliferation
Biological Process GO:0050765 negative regulation of phagocytosis
Biological Process GO:0050771 negative regulation of axonogenesis
Biological Process GO:0050821 protein stabilization
Biological Process GO:0051091 positive regulation of DNA-binding transcription factor activity
Biological Process GO:0051548 negative regulation of keratinocyte migration
Biological Process GO:0051726 regulation of cell cycle
Biological Process GO:0051895 negative regulation of focal adhesion assembly
Biological Process GO:0051898 negative regulation of protein kinase B signaling
Biological Process GO:0060024 rhythmic synaptic transmission
Biological Process GO:0060044 negative regulation of cardiac muscle cell proliferation
Biological Process GO:0060070 canonical Wnt signaling pathway
Biological Process GO:0060074 synapse maturation
Biological Process GO:0060134 prepulse inhibition
Biological Process GO:0060179 male mating behavior
Biological Process GO:0060291 long-term synaptic potentiation
Biological Process GO:0060292 long-term synaptic depression
Biological Process GO:0060341 regulation of cellular localization
Biological Process GO:0060736 prostate gland growth
Biological Process GO:0060997 dendritic spine morphogenesis
Biological Process GO:0061002 negative regulation of dendritic spine morphogenesis
Biological Process GO:0070373 negative regulation of ERK1 and ERK2 cascade
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0071257 cellular response to electrical stimulus
Biological Process GO:0071361 cellular response to ethanol
Biological Process GO:0071456 cellular response to hypoxia
Biological Process GO:0090071 negative regulation of ribosome biogenesis
Biological Process GO:0090344 negative regulation of cell aging
Biological Process GO:0090394 negative regulation of excitatory postsynaptic potential
Biological Process GO:0097105 presynaptic membrane assembly
Biological Process GO:0097107 postsynaptic density assembly
Biological Process GO:1901017 negative regulation of potassium ion transmembrane transporter activity
Biological Process GO:1902807 negative regulation of cell cycle G1/S phase transition
Biological Process GO:1903690 negative regulation of wound healing, spreading of epidermal cells
Biological Process GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway
Biological Process GO:1904668 positive regulation of ubiquitin protein ligase activity
Biological Process GO:1904706 negative regulation of vascular smooth muscle cell proliferation
Biological Process GO:1990314 cellular response to insulin-like growth factor stimulus
Biological Process GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process
Biological Process GO:2000134 negative regulation of G1/S transition of mitotic cell cycle
Biological Process GO:2000272 negative regulation of signaling receptor activity
Biological Process GO:2000463 positive regulation of excitatory postsynaptic potential
Biological Process GO:2000808 negative regulation of synaptic vesicle clustering
Biological Process GO:2001235 positive regulation of apoptotic signaling pathway
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005886 plasma membrane
Cellular Component GO:0009898 cytoplasmic side of plasma membrane
Cellular Component GO:0016324 apical plasma membrane
Cellular Component GO:0035749 myelin sheath adaxonal region
Cellular Component GO:0042995 cell projection
Cellular Component GO:0043005 neuron projection
Cellular Component GO:0043197 dendritic spine
Cellular Component GO:0043220 Schmidt-Lanterman incisure
Cellular Component GO:0045211 postsynaptic membrane
Cellular Component GO:0099524 postsynaptic cytosol
Molecular Function GO:0004438 phosphatidylinositol-3-phosphatase activity
Molecular Function GO:0004721 phosphoprotein phosphatase activity
Molecular Function GO:0004722 protein serine/threonine phosphatase activity
Molecular Function GO:0004725 protein tyrosine phosphatase activity
Molecular Function GO:0005161 platelet-derived growth factor receptor binding
Molecular Function GO:0005515 protein binding
Molecular Function GO:0008138 protein tyrosine/serine/threonine phosphatase activity
Molecular Function GO:0010997 anaphase-promoting complex binding
Molecular Function GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
Molecular Function GO:0016787 hydrolase activity
Molecular Function GO:0019899 enzyme binding
Molecular Function GO:0019901 protein kinase binding
Molecular Function GO:0030165 PDZ domain binding
Molecular Function GO:0035255 ionotropic glutamate receptor binding
Molecular Function GO:0042802 identical protein binding
Molecular Function GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
Molecular Function GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
Molecular Function GO:1990381 ubiquitin-specific protease binding
Molecular Function GO:1990782 protein tyrosine kinase binding

Gene - GO associations are updated daily from MGI


The KOMP Repository Collection is located at the MMRRC at the University of California, Davis and Children’s Hospital Oakland Research Institute. Question? Comments? For Mice, Cells, and germplasm please contact us at mmrrc@ucdavis.edu, US 1-888-KOMP-MICE or International +1-530-752-KOMP, or for vectors komporders@chori.org or +1-510-450-7917.