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KOMP Repository (Knockout Mouse Project) KOMP Knock Out Knockout Mouse Mice
GO Terms found for Il6
interleukin 6:

Biological Process GO:0001781 neutrophil apoptotic process
Biological Process GO:0002262 myeloid cell homeostasis
Biological Process GO:0002384 hepatic immune response
Biological Process GO:0002675 positive regulation of acute inflammatory response
Biological Process GO:0006469 negative regulation of protein kinase activity
Biological Process GO:0006953 acute-phase response
Biological Process GO:0006954 inflammatory response
Biological Process GO:0006955 immune response
Biological Process GO:0008284 positive regulation of cell proliferation
Biological Process GO:0008285 negative regulation of cell proliferation
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0009611 response to wounding
Biological Process GO:0010574 regulation of vascular endothelial growth factor production
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0010976 positive regulation of neuron projection development
Biological Process GO:0019221 cytokine-mediated signaling pathway
Biological Process GO:0031018 endocrine pancreas development
Biological Process GO:0031175 neuron projection development
Biological Process GO:0032722 positive regulation of chemokine production
Biological Process GO:0032755 positive regulation of interleukin-6 production
Biological Process GO:0032966 negative regulation of collagen biosynthetic process
Biological Process GO:0033138 positive regulation of peptidyl-serine phosphorylation
Biological Process GO:0033160 positive regulation of protein import into nucleus, translocation
Biological Process GO:0035729 cellular response to hepatocyte growth factor stimulus
Biological Process GO:0042102 positive regulation of T cell proliferation
Biological Process GO:0042110 T cell activation
Biological Process GO:0042127 regulation of cell proliferation
Biological Process GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
Biological Process GO:0042593 glucose homeostasis
Biological Process GO:0042832 defense response to protozoan
Biological Process GO:0042981 regulation of apoptotic process
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0045079 negative regulation of chemokine biosynthetic process
Biological Process GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep
Biological Process GO:0045429 positive regulation of nitric oxide biosynthetic process
Biological Process GO:0045454 cell redox homeostasis
Biological Process GO:0045630 positive regulation of T-helper 2 cell differentiation
Biological Process GO:0045666 positive regulation of neuron differentiation
Biological Process GO:0045721 negative regulation of gluconeogenesis
Biological Process GO:0045727 positive regulation of translation
Biological Process GO:0045740 positive regulation of DNA replication
Biological Process GO:0045779 negative regulation of bone resorption
Biological Process GO:0045837 negative regulation of membrane potential
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0046427 positive regulation of JAK-STAT cascade
Biological Process GO:0046716 muscle cell cellular homeostasis
Biological Process GO:0046888 negative regulation of hormone secretion
Biological Process GO:0048635 negative regulation of muscle organ development
Biological Process GO:0048661 positive regulation of smooth muscle cell proliferation
Biological Process GO:0050679 positive regulation of epithelial cell proliferation
Biological Process GO:0050710 negative regulation of cytokine secretion
Biological Process GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
Biological Process GO:0050871 positive regulation of B cell activation
Biological Process GO:0051024 positive regulation of immunoglobulin secretion
Biological Process GO:0051091 positive regulation of DNA-binding transcription factor activity
Biological Process GO:0051384 response to glucocorticoid
Biological Process GO:0051607 defense response to virus
Biological Process GO:0051897 positive regulation of protein kinase B signaling
Biological Process GO:0051971 positive regulation of transmission of nerve impulse
Biological Process GO:0060252 positive regulation of glial cell proliferation
Biological Process GO:0060445 branching involved in salivary gland morphogenesis
Biological Process GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis
Biological Process GO:0070091 glucagon secretion
Biological Process GO:0070102 interleukin-6-mediated signaling pathway
Biological Process GO:0070301 cellular response to hydrogen peroxide
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0071222 cellular response to lipopolysaccharide
Biological Process GO:0071347 cellular response to interleukin-1
Biological Process GO:0071356 cellular response to tumor necrosis factor
Biological Process GO:0071864 positive regulation of cell proliferation in bone marrow
Biological Process GO:0072540 T-helper 17 cell lineage commitment
Biological Process GO:1901215 negative regulation of neuron death
Biological Process GO:2000553 positive regulation of T-helper 2 cell cytokine production
Biological Process GO:2000660 negative regulation of interleukin-1-mediated signaling pathway
Cellular Component GO:0005576 extracellular region
Cellular Component GO:0005615 extracellular space
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005896 interleukin-6 receptor complex
Cellular Component GO:0009897 external side of plasma membrane
Molecular Function GO:0005102 signaling receptor binding
Molecular Function GO:0005125 cytokine activity
Molecular Function GO:0005138 interleukin-6 receptor binding
Molecular Function GO:0005515 protein binding
Molecular Function GO:0008083 growth factor activity

Gene - GO associations are updated daily from MGI


The KOMP Repository is located at the University of California Davis and Children’s Hospital Oakland Research Institute. Question? Comments? For Mice, Cells, and germplasm please contact us at service@komp.org, US 1-888-KOMP-MICE or International +1-530-752-KOMP, or for vectors komporders@chori.org or +1-510-450-7917.