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KOMP Repository (Knockout Mouse Project) KOMP Knock Out Knockout Mouse Mice
GO Terms found for Igfbp3
insulin-like growth factor binding protein 3:

Biological Process GO:0001558 regulation of cell growth
Biological Process GO:0001933 negative regulation of protein phosphorylation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0010666 positive regulation of cardiac muscle cell apoptotic process
Biological Process GO:0010906 regulation of glucose metabolic process
Biological Process GO:0014912 negative regulation of smooth muscle cell migration
Biological Process GO:0040008 regulation of growth
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0043567 regulation of insulin-like growth factor receptor signaling pathway
Biological Process GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway
Biological Process GO:0044342 type B pancreatic cell proliferation
Biological Process GO:0045663 positive regulation of myoblast differentiation
Biological Process GO:0048662 negative regulation of smooth muscle cell proliferation
Biological Process GO:1902512 positive regulation of apoptotic DNA fragmentation
Biological Process GO:2000844 negative regulation of testosterone secretion
Biological Process GO:0001649 osteoblast differentiation
Cellular Component GO:0005576 extracellular region
Cellular Component GO:0005615 extracellular space
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005720 nuclear heterochromatin
Cellular Component GO:0031091 platelet alpha granule
Cellular Component GO:0042567 insulin-like growth factor ternary complex
Cellular Component GO:0042568 insulin-like growth factor binary complex
Molecular Function GO:0001968 fibronectin binding
Molecular Function GO:0005520 insulin-like growth factor binding
Molecular Function GO:0008160 protein tyrosine phosphatase activator activity
Molecular Function GO:0019838 growth factor binding
Molecular Function GO:0031994 insulin-like growth factor I binding
Molecular Function GO:0031995 insulin-like growth factor II binding

Gene - GO associations are updated daily from MGI

The KOMP Repository Collection is located at the MMRRC at the University of California, Davis and Children’s Hospital Oakland Research Institute. Question? Comments? For Mice, Cells, and germplasm please contact us at mmrrc@ucdavis.edu, US 1-888-KOMP-MICE or International +1-530-752-KOMP, or for vectors komporders@chori.org or +1-510-450-7917.