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KOMP Repository (Knockout Mouse Project) KOMP Knock Out Knockout Mouse Mice
GO Terms found for Cd74
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated):

Biological Process GO:0000187 activation of MAPK activity
Biological Process GO:0001516 prostaglandin biosynthetic process
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0001961 positive regulation of cytokine-mediated signaling pathway
Biological Process GO:0002250 adaptive immune response
Biological Process GO:0002376 immune system process
Biological Process GO:0002606 positive regulation of dendritic cell antigen processing and presentation
Biological Process GO:0002792 negative regulation of peptide secretion
Biological Process GO:0002821 positive regulation of adaptive immune response
Biological Process GO:0002830 positive regulation of type 2 immune response
Biological Process GO:0002906 negative regulation of mature B cell apoptotic process
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0006952 defense response
Biological Process GO:0006955 immune response
Biological Process GO:0008283 cell population proliferation
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0016064 immunoglobulin mediated immune response
Biological Process GO:0019882 antigen processing and presentation
Biological Process GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
Biological Process GO:0030336 negative regulation of cell migration
Biological Process GO:0030890 positive regulation of B cell proliferation
Biological Process GO:0031394 positive regulation of prostaglandin biosynthetic process
Biological Process GO:0033674 positive regulation of kinase activity
Biological Process GO:0035691 macrophage migration inhibitory factor signaling pathway
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator
Biological Process GO:0045059 positive thymic T cell selection
Biological Process GO:0045060 negative thymic T cell selection
Biological Process GO:0045080 positive regulation of chemokine biosynthetic process
Biological Process GO:0045089 positive regulation of innate immune response
Biological Process GO:0045410 positive regulation of interleukin-6 biosynthetic process
Biological Process GO:0045416 positive regulation of interleukin-8 biosynthetic process
Biological Process GO:0045581 negative regulation of T cell differentiation
Biological Process GO:0045582 positive regulation of T cell differentiation
Biological Process GO:0045657 positive regulation of monocyte differentiation
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0046598 positive regulation of viral entry into host cell
Biological Process GO:0048146 positive regulation of fibroblast proliferation
Biological Process GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
Biological Process GO:0051085 chaperone cofactor-dependent protein refolding
Biological Process GO:0051290 protein heterotetramerization
Biological Process GO:0060907 positive regulation of macrophage cytokine production
Biological Process GO:0065003 protein-containing complex assembly
Biological Process GO:0070206 protein trimerization
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0090023 positive regulation of neutrophil chemotaxis
Biological Process GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Biological Process GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production
Biological Process GO:2000448 positive regulation of macrophage migration inhibitory factor signaling pathway
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005764 lysosome
Cellular Component GO:0005770 late endosome
Cellular Component GO:0005771 multivesicular body
Cellular Component GO:0005773 vacuole
Cellular Component GO:0005783 endoplasmic reticulum
Cellular Component GO:0005794 Golgi apparatus
Cellular Component GO:0005886 plasma membrane
Cellular Component GO:0005887 integral component of plasma membrane
Cellular Component GO:0009897 external side of plasma membrane
Cellular Component GO:0009986 cell surface
Cellular Component GO:0016020 membrane
Cellular Component GO:0016021 integral component of membrane
Cellular Component GO:0032991 protein-containing complex
Cellular Component GO:0035692 macrophage migration inhibitory factor receptor complex
Cellular Component GO:0035693 NOS2-CD74 complex
Cellular Component GO:0042613 MHC class II protein complex
Molecular Function GO:0001540 amyloid-beta binding
Molecular Function GO:0004896 cytokine receptor activity
Molecular Function GO:0005515 protein binding
Molecular Function GO:0019955 cytokine binding
Molecular Function GO:0023026 MHC class II protein complex binding
Molecular Function GO:0035718 macrophage migration inhibitory factor binding
Molecular Function GO:0042289 MHC class II protein binding
Molecular Function GO:0042609 CD4 receptor binding
Molecular Function GO:0042658 MHC class II protein binding, via antigen binding groove
Molecular Function GO:0044183 protein folding chaperone
Molecular Function GO:0050998 nitric-oxide synthase binding

Gene - GO associations are updated daily from MGI

The KOMP Repository Collection is located at the MMRRC at the University of California, Davis and Children’s Hospital Oakland Research Institute. Question? Comments? For Mice, Cells, and germplasm please contact us at mmrrc@ucdavis.edu, US 1-888-KOMP-MICE or International +1-530-752-KOMP, or for vectors komporders@chori.org or +1-510-450-7917.