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KOMP Repository (Knockout Mouse Project) KOMP Knock Out Knockout Mouse Mice
GO Terms found for Apaf1
apoptotic peptidase activating factor 1:

Biological Process GO:0001843 neural tube closure
Biological Process GO:0006915 apoptotic process
Biological Process GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0007275 multicellular organism development
Biological Process GO:0007420 brain development
Biological Process GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
Biological Process GO:0010659 cardiac muscle cell apoptotic process
Biological Process GO:0030900 forebrain development
Biological Process GO:0042981 regulation of apoptotic process
Biological Process GO:0051402 neuron apoptotic process
Biological Process GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Biological Process GO:0071560 cellular response to transforming growth factor beta stimulus
Biological Process GO:0097190 apoptotic signaling pathway
Biological Process GO:1902510 regulation of apoptotic DNA fragmentation
Biological Process GO:2001235 positive regulation of apoptotic signaling pathway
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0032991 protein-containing complex
Cellular Component GO:0043293 apoptosome
Molecular Function GO:0000166 nucleotide binding
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process
Molecular Function GO:0031072 heat shock protein binding
Molecular Function GO:0042802 identical protein binding
Molecular Function GO:0043531 ADP binding

Gene - GO associations are updated daily from MGI

The KOMP Repository Collection is located at the MMRRC at the University of California Davis. Question? Comments? Please contact us at mmrrc@ucdavis.edu, US 1-888-566-7643 or International +1-530-754-6677.