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KOMP Repository (Knockout Mouse Project) KOMP Knock Out Knockout Mouse Mice
GO Terms found for Apaf1
apoptotic peptidase activating factor 1:

Biological Process GO:0001843 neural tube closure
Biological Process GO:0006915 apoptotic process
Biological Process GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0007275 multicellular organism development
Biological Process GO:0007420 brain development
Biological Process GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
Biological Process GO:0010659 cardiac muscle cell apoptotic process
Biological Process GO:0030900 forebrain development
Biological Process GO:0042981 regulation of apoptotic process
Biological Process GO:0051402 neuron apoptotic process
Biological Process GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Biological Process GO:0071560 cellular response to transforming growth factor beta stimulus
Biological Process GO:0097190 apoptotic signaling pathway
Biological Process GO:1902510 regulation of apoptotic DNA fragmentation
Biological Process GO:2001235 positive regulation of apoptotic signaling pathway
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0032991 protein-containing complex
Cellular Component GO:0043293 apoptosome
Molecular Function GO:0000166 nucleotide binding
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process
Molecular Function GO:0031072 heat shock protein binding
Molecular Function GO:0042802 identical protein binding
Molecular Function GO:0043531 ADP binding

Gene - GO associations are updated daily from MGI

The KOMP Repository Collection is located at the MMRRC at the University of California, Davis and Children’s Hospital Oakland Research Institute. Question? Comments? For Mice, Cells, and germplasm please contact us at mmrrc@ucdavis.edu, US 1-888-KOMP-MICE or International +1-530-752-KOMP, or for vectors komporders@chori.org or +1-510-450-7917.