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KOMP Repository (Knockout Mouse Project) KOMP Knock Out Knockout Mouse Mice
GO Terms found for Alox5
arachidonate 5-lipoxygenase:

Biological Process GO:0001937 negative regulation of endothelial cell proliferation
Biological Process GO:0002232 leukocyte chemotaxis involved in inflammatory response
Biological Process GO:0002523 leukocyte migration involved in inflammatory response
Biological Process GO:0002526 acute inflammatory response
Biological Process GO:0002540 leukotriene production involved in inflammatory response
Biological Process GO:0006691 leukotriene metabolic process
Biological Process GO:0006954 inflammatory response
Biological Process GO:0006959 humoral immune response
Biological Process GO:0016525 negative regulation of angiogenesis
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0019370 leukotriene biosynthetic process
Biological Process GO:0030501 positive regulation of bone mineralization
Biological Process GO:0036336 dendritic cell migration
Biological Process GO:0042593 glucose homeostasis
Biological Process GO:0045598 regulation of fat cell differentiation
Biological Process GO:0045907 positive regulation of vasoconstriction
Biological Process GO:0050727 regulation of inflammatory response
Biological Process GO:0050728 negative regulation of inflammatory response
Biological Process GO:0050796 regulation of insulin secretion
Biological Process GO:0055114 oxidation-reduction process
Biological Process GO:0061044 negative regulation of vascular wound healing
Biological Process GO:0061045 negative regulation of wound healing
Biological Process GO:0106014 regulation of inflammatory response to wounding
Biological Process GO:1900015 regulation of cytokine production involved in inflammatory response
Biological Process GO:1900407 regulation of cellular response to oxidative stress
Biological Process GO:1901753 leukotriene A4 biosynthetic process
Biological Process GO:1903426 regulation of reactive oxygen species biosynthetic process
Biological Process GO:1903573 negative regulation of response to endoplasmic reticulum stress
Biological Process GO:1903671 negative regulation of sprouting angiogenesis
Biological Process GO:1904960 positive regulation of cytochrome-c oxidase activity
Biological Process GO:1904999 positive regulation of leukocyte adhesion to arterial endothelial cell
Biological Process GO:2001301 lipoxin biosynthetic process
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005635 nuclear envelope
Cellular Component GO:0005641 nuclear envelope lumen
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0016020 membrane
Cellular Component GO:0016363 nuclear matrix
Cellular Component GO:0030425 dendrite
Cellular Component GO:0031965 nuclear membrane
Cellular Component GO:0042383 sarcolemma
Cellular Component GO:0048471 perinuclear region of cytoplasm
Molecular Function GO:0004051 arachidonate 5-lipoxygenase activity
Molecular Function GO:0005506 iron ion binding
Molecular Function GO:0005515 protein binding
Molecular Function GO:0016491 oxidoreductase activity
Molecular Function GO:0016787 hydrolase activity
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0051213 dioxygenase activity

Gene - GO associations are updated daily from MGI

The KOMP Repository Collection is located at the MMRRC at the University of California, Davis and Children’s Hospital Oakland Research Institute. Question? Comments? For Mice, Cells, and germplasm please contact us at mmrrc@ucdavis.edu, US 1-888-KOMP-MICE or International +1-530-752-KOMP, or for vectors komporders@chori.org or +1-510-450-7917.