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KOMP Repository (Knockout Mouse Project) KOMP Knock Out Knockout Mouse Mice
GO Terms found for Adam17
a disintegrin and metallopeptidase domain 17:

Biological Process GO:0001666 response to hypoxia
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0002467 germinal center formation
Biological Process GO:0002532 production of molecular mediator involved in inflammatory response
Biological Process GO:0006508 proteolysis
Biological Process GO:0006509 membrane protein ectodomain proteolysis
Biological Process GO:0007155 cell adhesion
Biological Process GO:0007173 epidermal growth factor receptor signaling pathway
Biological Process GO:0007219 Notch signaling pathway
Biological Process GO:0007220 Notch receptor processing
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0010820 positive regulation of T cell chemotaxis
Biological Process GO:0010976 positive regulation of neuron projection development
Biological Process GO:0010977 negative regulation of neuron projection development
Biological Process GO:0030183 B cell differentiation
Biological Process GO:0030307 positive regulation of cell growth
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
Biological Process GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0032722 positive regulation of chemokine production
Biological Process GO:0033025 regulation of mast cell apoptotic process
Biological Process GO:0033077 T cell differentiation in thymus
Biological Process GO:0033627 cell adhesion mediated by integrin
Biological Process GO:0035624 receptor transactivation
Biological Process GO:0042493 response to drug
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0043536 positive regulation of blood vessel endothelial cell migration
Biological Process GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity
Biological Process GO:0045741 positive regulation of epidermal growth factor-activated receptor activity
Biological Process GO:0048536 spleen development
Biological Process GO:0048679 regulation of axon regeneration
Biological Process GO:0048870 cell motility
Biological Process GO:0050830 defense response to Gram-positive bacterium
Biological Process GO:0051088 PMA-inducible membrane protein ectodomain proteolysis
Biological Process GO:0051272 positive regulation of cellular component movement
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0071403 cellular response to high density lipoprotein particle stimulus
Biological Process GO:0120163 negative regulation of cold-induced thermogenesis
Biological Process GO:1900087 positive regulation of G1/S transition of mitotic cell cycle
Biological Process GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway
Biological Process GO:1905564 positive regulation of vascular endothelial cell proliferation
Biological Process GO:2001222 regulation of neuron migration
Cellular Component GO:0005576 extracellular region
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005886 plasma membrane
Cellular Component GO:0005887 integral component of plasma membrane
Cellular Component GO:0005911 cell-cell junction
Cellular Component GO:0005925 focal adhesion
Cellular Component GO:0009986 cell surface
Cellular Component GO:0015629 actin cytoskeleton
Cellular Component GO:0016020 membrane
Cellular Component GO:0016021 integral component of membrane
Cellular Component GO:0016324 apical plasma membrane
Cellular Component GO:0031410 cytoplasmic vesicle
Cellular Component GO:0032587 ruffle membrane
Cellular Component GO:0045121 membrane raft
Cellular Component GO:0045177 apical part of cell
Molecular Function GO:0004175 endopeptidase activity
Molecular Function GO:0004222 metalloendopeptidase activity
Molecular Function GO:0005112 Notch binding
Molecular Function GO:0005138 interleukin-6 receptor binding
Molecular Function GO:0005178 integrin binding
Molecular Function GO:0005515 protein binding
Molecular Function GO:0008233 peptidase activity
Molecular Function GO:0008237 metallopeptidase activity
Molecular Function GO:0016787 hydrolase activity
Molecular Function GO:0017124 SH3 domain binding
Molecular Function GO:0030165 PDZ domain binding
Molecular Function GO:0046872 metal ion binding

Gene - GO associations are updated daily from MGI

The KOMP Repository Collection is located at the MMRRC at the University of California, Davis and Children’s Hospital Oakland Research Institute. Question? Comments? For Mice, Cells, and germplasm please contact us at mmrrc@ucdavis.edu, US 1-888-KOMP-MICE or International +1-530-752-KOMP, or for vectors komporders@chori.org or +1-510-450-7917.