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KOMP Repository (Knockout Mouse Project) KOMP Knock Out Knockout Mouse Mice
GO Terms found for Abl1
c-abl oncogene 1, non-receptor tyrosine kinase:

Biological Process GO:0001843 neural tube closure
Biological Process GO:0001922 B-1 B cell homeostasis
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0002322 B cell proliferation involved in immune response
Biological Process GO:0002333 transitional one stage B cell differentiation
Biological Process GO:0006281 DNA repair
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0006897 endocytosis
Biological Process GO:0006909 phagocytosis
Biological Process GO:0006914 autophagy
Biological Process GO:0006915 apoptotic process
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0006975 DNA damage induced protein phosphorylation
Biological Process GO:0006979 response to oxidative stress
Biological Process GO:0007155 cell adhesion
Biological Process GO:0007173 epidermal growth factor receptor signaling pathway
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0007229 integrin-mediated signaling pathway
Biological Process GO:0009791 post-embryonic development
Biological Process GO:0010595 positive regulation of endothelial cell migration
Biological Process GO:0016310 phosphorylation
Biological Process GO:0018108 peptidyl-tyrosine phosphorylation
Biological Process GO:0021587 cerebellum morphogenesis
Biological Process GO:0022408 negative regulation of cell-cell adhesion
Biological Process GO:0030035 microspike assembly
Biological Process GO:0030036 actin cytoskeleton organization
Biological Process GO:0030182 neuron differentiation
Biological Process GO:0030514 negative regulation of BMP signaling pathway
Biological Process GO:0030516 regulation of axon extension
Biological Process GO:0031113 regulation of microtubule polymerization
Biological Process GO:0032489 regulation of Cdc42 protein signal transduction
Biological Process GO:0032729 positive regulation of interferon-gamma production
Biological Process GO:0032743 positive regulation of interleukin-2 production
Biological Process GO:0032956 regulation of actin cytoskeleton organization
Biological Process GO:0033690 positive regulation of osteoblast proliferation
Biological Process GO:0034446 substrate adhesion-dependent cell spreading
Biological Process GO:0035791 platelet-derived growth factor receptor-beta signaling pathway
Biological Process GO:0038083 peptidyl-tyrosine autophosphorylation
Biological Process GO:0038189 neuropilin signaling pathway
Biological Process GO:0042100 B cell proliferation
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0042770 signal transduction in response to DNA damage
Biological Process GO:0042981 regulation of apoptotic process
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0043542 endothelial cell migration
Biological Process GO:0045184 establishment of protein localization
Biological Process GO:0045580 regulation of T cell differentiation
Biological Process GO:0045930 negative regulation of mitotic cell cycle
Biological Process GO:0045931 positive regulation of mitotic cell cycle
Biological Process GO:0046632 alpha-beta T cell differentiation
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0048008 platelet-derived growth factor receptor signaling pathway
Biological Process GO:0048536 spleen development
Biological Process GO:0048538 thymus development
Biological Process GO:0048668 collateral sprouting
Biological Process GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
Biological Process GO:0050798 activated T cell proliferation
Biological Process GO:0050852 T cell receptor signaling pathway
Biological Process GO:0050853 B cell receptor signaling pathway
Biological Process GO:0050885 neuromuscular process controlling balance
Biological Process GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
Biological Process GO:0051353 positive regulation of oxidoreductase activity
Biological Process GO:0051444 negative regulation of ubiquitin-protein transferase activity
Biological Process GO:0051496 positive regulation of stress fiber assembly
Biological Process GO:0051726 regulation of cell cycle
Biological Process GO:0051894 positive regulation of focal adhesion assembly
Biological Process GO:0060020 Bergmann glial cell differentiation
Biological Process GO:0060563 neuroepithelial cell differentiation
Biological Process GO:0070301 cellular response to hydrogen peroxide
Biological Process GO:0070373 negative regulation of ERK1 and ERK2 cascade
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0071103 DNA conformation change
Biological Process GO:0071222 cellular response to lipopolysaccharide
Biological Process GO:0071901 negative regulation of protein serine/threonine kinase activity
Biological Process GO:0072359 circulatory system development
Biological Process GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis
Biological Process GO:0090135 actin filament branching
Biological Process GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
Biological Process GO:1900272 negative regulation of long-term synaptic potentiation
Biological Process GO:1900275 negative regulation of phospholipase C activity
Biological Process GO:1901216 positive regulation of neuron death
Biological Process GO:1903053 regulation of extracellular matrix organization
Biological Process GO:1904528 positive regulation of microtubule binding
Biological Process GO:1904531 positive regulation of actin filament binding
Biological Process GO:1905244 regulation of modification of synaptic structure
Biological Process GO:1905555 positive regulation blood vessel branching
Biological Process GO:1990051 activation of protein kinase C activity
Biological Process GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway
Biological Process GO:2000251 positive regulation of actin cytoskeleton reorganization
Biological Process GO:2000352 negative regulation of endothelial cell apoptotic process
Biological Process GO:2000772 regulation of cellular senescence
Biological Process GO:2000773 negative regulation of cellular senescence
Biological Process GO:2001020 regulation of response to DNA damage stimulus
Cellular Component GO:0001726 ruffle
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0005783 endoplasmic reticulum
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005856 cytoskeleton
Cellular Component GO:0015629 actin cytoskeleton
Cellular Component GO:0016604 nuclear body
Cellular Component GO:0030425 dendrite
Cellular Component GO:0030426 growth cone
Cellular Component GO:0031252 cell leading edge
Cellular Component GO:0032991 protein-containing complex
Cellular Component GO:0043005 neuron projection
Cellular Component GO:0043025 neuronal cell body
Cellular Component GO:0045202 synapse
Cellular Component GO:0048471 perinuclear region of cytoplasm
Molecular Function GO:0000166 nucleotide binding
Molecular Function GO:0000287 magnesium ion binding
Molecular Function GO:0000400 four-way junction DNA binding
Molecular Function GO:0000405 bubble DNA binding
Molecular Function GO:0001784 phosphotyrosine residue binding
Molecular Function GO:0003677 DNA binding
Molecular Function GO:0004672 protein kinase activity
Molecular Function GO:0004713 protein tyrosine kinase activity
Molecular Function GO:0004715 non-membrane spanning protein tyrosine kinase activity
Molecular Function GO:0005080 protein kinase C binding
Molecular Function GO:0005515 protein binding
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0008022 protein C-terminus binding
Molecular Function GO:0016301 kinase activity
Molecular Function GO:0016740 transferase activity
Molecular Function GO:0017124 SH3 domain binding
Molecular Function GO:0019901 protein kinase binding
Molecular Function GO:0019904 protein domain specific binding
Molecular Function GO:0019905 syntaxin binding
Molecular Function GO:0030145 manganese ion binding
Molecular Function GO:0038191 neuropilin binding
Molecular Function GO:0042169 SH2 domain binding
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0046875 ephrin receptor binding
Molecular Function GO:0051015 actin filament binding
Molecular Function GO:0051019 mitogen-activated protein kinase binding
Molecular Function GO:0070064 proline-rich region binding
Molecular Function GO:0070097 delta-catenin binding
Molecular Function GO:1990837 sequence-specific double-stranded DNA binding

Gene - GO associations are updated daily from MGI

The KOMP Repository Collection is located at the MMRRC at the University of California, Davis and Children’s Hospital Oakland Research Institute. Question? Comments? For Mice, Cells, and germplasm please contact us at mmrrc@ucdavis.edu, US 1-888-KOMP-MICE or International +1-530-752-KOMP, or for vectors komporders@chori.org or +1-510-450-7917.